ASP Scan (Weekly) for Jan 26, 2018

first_imgOur weekly wrap-up of antimicrobial stewardship & antimicrobial resistance scansUK health officials advise against antibiotics for acute sore throatNew guidance today from the United Kingdom’s National Institute for Health and Care Excellence (NICE) and Public Health England says general practitioners should not offer, and patients should not expect, antibiotics in most cases of acute sore throat.The recommendations, aimed at limiting antibiotic use and reducing antimicrobial resistance, explain that acute sore throat (including pharyngitis and tonsillitis) is often self-limiting, most frequently triggered by a viral infection of the upper respiratory tract, and that most people will get better within a week without antibiotics. They advise physicians to explain to patients the usual course of acute sore throat and to recommend tips for management of symptoms. They also advise patients to seek medical help if symptoms worsen rapidly or don’t improve after a week.The guidance also lays out criteria for physicians to use when evaluating patients with acute sore throat. It recommends that patients who score low on clinical criteria scoring systems (0 or 1 points on FeverPAIN or 0,1, or 2 on Centor) should not receive an antibiotic and should be advised to drink adequate fluids and consider pain relievers and medicated lozenges. Patients with FeverPAIN scores of 2 or 3 should be given a back-up antibiotic prescription if their symptoms don’t improve in 3 to 5 days. For patients most likely to benefit from an antibiotic (those with a FeverPAIN score or 4 or 5 or a Centor score of 3 or 4), the guidance calls for an immediate antibiotic, taking into account possible adverse effects and the unlikely event of complications if antibiotics are withheld.”We are living in a world where bacteria are becoming more resistant to antibiotics,” Gillian Leng, deputy chief executive at NICE, told the BBC. “It is vital these medicines are protected, and only used when they are effective.”Jan 26 NICE guidance on acute sore throatJan 26 BBC story Australian scientists find potential in a neglected class of antibioticsAustralian scientists report that a synthetic version of a neglected class of antibiotics showed efficacy against multidrug-resistant (MDR) bacteria in preclinical tests, according to a study today in Cell Chemical Biology.In the study, scientists from the University of Queensland identified the biosynthetic pathway of octapeptins, a family of lipopeptide antibiotics that were discovered nearly four decades ago and are structurally related to the last-resort antibiotic colistin. Octapeptins displayed activity against gram-negative bacteria in several studies but were ultimately neglected due to a proliferation of other antibiotics.In vitro testing against a panel of MDR bacteria revealed that one of the octapeptins identified, octapeptin C4, was more effective than colisitin against polymixin-resistant isolates of Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae, but was not as effective against polymixin-resistant P aeruginosa in a mouse blood infection model, most likely due to high plasma protein binding. The scientists then designed a synthetic octapeptin with a similar structure to octapeptin C4 but reduced plasma protein binding that showed dramatically improved in vivo activity.”Our in vitro and in vivo efficacy data indicate the significant potential of novel octapeptin-like lipopeptides as new antibiotics against polymyxin-resistant Gram-negative superbugs,” the authors of the study write. They also note that octapeptins are potentially less toxic to the kidneys than colistin and polymixin BJan 26 Cell Chem Biol abstract Consumer group urges McDonald’s to detail an antibiotic-free-meat planAs part of the launch of a national campaign, the consumer and public health advocacy group US PIRG Education Fund is calling on McDonald’s Corp to commit to a specific timeline to phase out routine use of medically important antibiotics in its beef and pork supply chain, US PIRG (Public Interest Research Group) said in a news release yesterday.The organization is spotlighting McDonald’s because of its “outsized influence” as the largest US buyer of beef and has only a vague long-term antibiotics plan. Public health experts across the globe have warned that routine use of antibiotics in food animals helps spur antimicrobial resistance in a wide range of pathogens and poses a distinct threat to people.”Protecting antibiotics requires action, not reaction. If we don’t act now to preserve the effectiveness of these medicines, we’ll face a world in which common infections once again kill,” said Matthew Wellington, antibiotics program director for US PIRG Education Fund. “The Big Mac can make a big dent in stopping the misuse of antibiotics in our food system,” he added, referring to McDonald’s flagship hamburger.As part of its “Hold the Antibiotics” campaign launch, US PIRG has had nearly 10,000 people sign a petition to support its efforts. The group’s state affiliates also held events in front of McDonald’s franchises across the country to educate people about the perils of antibiotic-resistant bacteria and the important role that McDonald’s can play.In August 2017, McDonald’s announced that it will phase out use of highest-value human antibiotics in its global chicken supply, after having reached its US goal of serving broiler chickens raised without antibiotics in 2016. It has also signaled that it would take similar actions for its supply of beef, dairy cows, pork, and laying hens.Jan 25 US PIRG news releaseAug 24, 2017, CIDRAP News story “McDonald’s expands antibiotic-cutting steps globally” Officials in India announce world’s first drug-resistant typhoid outbreakOriginally published by CIDRAP News Jan 25In what is being called the world’s first outbreak of drug-resistant typhoid, more than 100 children are sick and dozens have died in Hyderabad, India, The News International, which is based in Pakistan, reported yesterday.”Typhoid cases resistant to third-generation antibiotic Ceftriaxone have been reported from different areas of Hyderabad, but so far we’re unable to find its source,” Health Services Sindh Director General Dr Muhammad Akhlaq Khan said.”Children in the age group of 2-10 years are being affected by this type of disease, but so far we don’t have any exact data on the deaths caused by this lethal disease.” Scientists at Aga Khan University (AKU) in Karachi, Pakistan, blamed the outbreak on contaminated water, but the Sindh Health Department has ruled that cause out, the story said.No official case count has been cited, but the city’s health department and local gastroenterologists have said more than 100 drug-resistant cases have been reported since November 2016, compared with only 6 cases from 2009 to 2014. The health department, in collaboration with AKU, has launched a mass vaccination campaign aimed at immunizing 250,000 children in the district.Typhoid is mainly caused by Salmonella enterica serotype Typhi bacteria. About 8 million people live in the Hyderabad metropolitan area.Jan 24 News International story Bowel disease, antibiotics tied to fecal transplant for recurrent C difficileOriginally published by CIDRAP News Jan 25A single-center study in Rhode Island found several risk factors, including inflammatory bowel disease and the use of metronidazole, for fecal microbiota transplantation (FMT) to address recurrent Clostridium difficile infection (CDI), according to a study yesterday in Infection Control and Hospital Epidemiology.The retrospective study compared 200 adults who underwent FMT for recurrent CDI to 75 patients who did not. The strongest risk factors for FMT for recurrent CDI were concomitant inflammatory bowel disease (P = .002), use of immunosuppressive therapy (P = .04), and use of metronidazole within 2 months before the first CDI (P = .02). The use of vancomycin for the first CDI was also a potential risk factor.The authors concluded, “This study provides important insights into the factors predictive for FMT in patients with recurrent CDI and highlights the potential racial and medical characteristics that affect the access of the patients to FMT.”Jan 24 Infect Control Hosp Epidemiol study Study finds reduced carbapenem consumption in French hospitalsOriginally published by CIDRAP News Jan 23Researchers in France report that a reduction in carbapenem consumption in French hospitals occurred after the release of national guidelines on carbapenem use in 2010, according to a study yesterday in Antimicrobial Resistance and Infection Control. They suggest that further carbapenem reduction could be linked to reduced use of fluoroquinolones and third-generation cephalosporins (3GCs).The ward-level multicenter retrospective study, which sought to determine factors associated with reduced carbapenem use in intensive care units (ICUs), medical wards, and surgical wards from 2009 through 2013, was based on data from French surveillance networks of antibiotics and multidrug-resistant bacteria in healthcare facilities. France released guidelines to limit the use of carbapenems in 2010, in response to a rise in carbapenemase-producing Enterobacteriaceae that’s been driven in part by a 145% increase in carbapenem use since 2000. The increase in carbapenem use was in response to the spread of extended-spectrum beta-lactamase–producing Enterobacteriaceae (ESBL-PE).A total of 493 wards from 259 healthcare facilities were included in the study (85 ICUs, 227 medical wards, and 181 surgical wards). Overall carbapenem consumption over the study period was equal to 73.4 defined daily doses per 1,000 patient days for ICUs, compared with 6.2 in medical wards and 5.4 in surgical wards. While the overall trend showed an increase in carbapenem use from 2009 through 2013 in all wards, the period following release of the guidelines (2011-2013) showed a 2.9% decrease in carbapenem use in ICUs and 1.6% decrease in medical wards. Carbapenem use continued to rise in surgical wards, but the annual growth rate declined from 17.8% to 2.7%.In multivariable analysis, factors associated with a higher probability of reducing carbapenem consumption included a geographic location in eastern France, a higher initial carbapenem-prescribing profile, and reductions in consumption of fluoroquinolones, glycopeptides, and piperacillin/tazobactam. A higher initial prescribing profile for 3GCs and location in high-risk regions for ESBL-PEs were associated with a lower probability of reducing carbapenem use. The authors note that this finding is explained by ESBL-PE risk, which is promoted by 3GC use and thus leads to more frequent carbapenem prescribing.The authors conclude, “Our study, carried out on a national scale, in a large number of hospital wards, suggests that a decrease in 3GC proportion in the overall antibiotic use, as well as the continuation of the reduction in fluoroquinolone use, could allow reducing ward-level carbapenem use.” Jan 22 Antimicrob Resist Infect Control study CARB-X seeks partners to support antibiotic developmentOriginally published by CIDRAP News Jan 23CARB-X, the public-private initiative that provides financial and technical support to companies in the early stages of antibiotic discovery and development, is looking to partner with additional accelerator organizations to support its pipeline of research projects.According to a press release today from CARB-X (the Combating Antibiotic Resistant Bacteria Biopharmaceutical Accelerator), the new accelerators are expected to provide a broad range of support to the 22 active research projects in the Powered by CARB-X portfolio. CARB-X says more projects will be added in the coming months.”Our accelerator partners are essential to CARB-X’s mission, providing guidance and expertise to help partner companies accelerate their research and deliver new life-saving antibiotics, vaccines, diagnostics, and other products to patients,” CARB-X Executive Director Kevin Outterson, JD, said in the press release.To date, CARB-X has awarded more than $60 million to help fund early research in new antibiotics, vaccines, and rapid diagnostics to treat drug-resistant infections. The organization is looking to partner with up to six additional accelerator partners in Europe, North America, and the rest of the world. Jan 23 CARB-X press release Single-center study finds low levels of C difficile transmission in kidsOriginally published by CIDRAP News Jan 23A single-center Clostridium difficile infection (CDI) study from Northwestern University in Chicago found transmission among symptomatic children uncommon, and they noted that investigation of shared healthcare exposures often did not identify a potential transmission source, according to a study today in Clinical Infectious Diseases.The investigators performed whole-genome sequencing on C difficile isolates collected from children diagnosed as having CDI from December 2012 to December 2013. Among 131 CDIs in 107 children, the authors identified 104 genetically distinct isolates. Of 84 CDIs occurring 8 weeks or longer after the start of the study, only 10 (11.9%) were caused by a strain similar to another isolate, which would indicate likely in-hospital transmission. The researchers identified shared healthcare facility exposures in only 7 of those 10 cases.The authors conclude, “C. difficile transmission among symptomatic children was very uncommon, and among putatively transmitted cases, investigation of shared healthcare exposures often did not identify a potential transmission source.”Jan 23 Clin Infect Dis abstract Deadly outbreak of resistant Acinetobacter frequently involved pneumoniaOriginally published by CIDRAP News Jan 23A separate study yesterday in Antimicrobial Resistance and Infection Control determined that multidrug-resistant A baumannii (MDR-Ab) infections in a Beirut hospital from 2007 through 2014 mostly consisted of ventilator-associated pneumonia and killed up to two thirds of patients.The researchers conducted a case-control study after MDR-Ab cases more than doubled at the American University of Beirut Medical Center ICU in 2007. That study involved patients diagnosed as having MDR-Ab in 2007 and 2008. The team also conducted a prospective study of MDR-Ab spread in the ICU in 2007 through 2014. The studies included 128 cases collectively and 99 patients who had MDR-Ab colonization but no evidence of active infection.The vast majority—84%—of cases were deemed hospital acquired, and 53% were ventilator-associated pneumonia. Mortality rates ranged from 52% to 66%. The investigators listed a range because “it was difficult to calculate the attributable mortality due to the fact that many patients were critically ill with multiple comorbid conditions.”The authors concluded, “Infection control measures should be reinforced to control the transmission of these organisms in the ICU.”Jan 22 Antimicrob Resist Infect Control study C diff prevention initiative helps reduce rates in VA facilitiesOriginally published by CIDRAP News Jan 22A significant decrease in rates of clinically confirmed long-term care facility onset CDI at 132 Veteran’s Affairs facilities coincided with implementation of a nationwide prevention initiative, researchers report in a new study in Infection Control and Hospital Epidemiology.The initiative for prevention of CDI in VA long-term care facilities (LTCFs) was implemented in February 2014 following implementation in VA acute care facilities in July 2012. The initiative, which emphasizes environmental management, hand hygiene, contact precautions, and institutional culture change, was extended and tailored to VA LTCFs because they are often linked to VA acute care facilities, where CDI has become the most common healthcare-associated infection. To evaluate the impact of the initiative, the researchers analyzed quarterly CDI trends from the first 33 months of the program and compared them with the 2 years prior to implementation.The analysis found that there were 137,289 admissions, 9,288,098 resident days, and 1,373 clinically confirmed LTCF-onset CDI cases from April 2014 through December 2016. The nationwide number of clinically confirmed LTCF-onset CDI cases did not change in the 2 years prior to implementation of the prevention initiative but decreased by 36.1% over the 33-month analysis period.The results mirror the experience in VA acute care facilities, which saw a 15% drop in hospital-acquired CDI cases over the first 33 months of the prevention initiative, and the authors note that this may have had an impact on their findings, along with strong leadership from the VA Central Office and individual facility accountability. “The exact reason for the decrease in cases within the VA LTCFs is not known,” they write. “Given the large number of facilities involved and the long observation period, we were not able to collect data on individual facility activities or sustainability of activities; hence, we cannot report a ‘magic bullet’ responsible for the declining trend.”Jan 21 Infect Control Hosp Epidemiol abstract Study shows substantial burden of primary, recurrent C diffOriginally published by CIDRAP News Jan 22In another study on CDI, researchers with Merck’s Center for Observational and Real World Evidence estimated the healthcare resource utilization (HCRU) and costs attributable to primary CDI and recurrent CDI (rCDI).In the retrospective observational study, published in Clinical Infectious Diseases, the researchers analyzed administrative claims data from two commercial databases representing nearly 50 million individuals with private health insurance. To obtain hospitalized days and costs attributable to primary CDI, patients without CDI were matched 1:1 by propensity score to those with primary CDI but no recurrences. To obtain hospitalized days and costs associated with rCDI, patients with primary CDI but no recurrences were matched 1:1 to those with primary CDI plus one recurrence.A total of 55,504 CDI patients were identified from July 2010 through June 2014, and among those patients 24.8% had a recurrence. Compared to those patients without CDI, the cumulative hospitalized days and healthcare costs attributable to primary CDI were 5.20 days and $24,205. Compared to those patients with primary CDI only, the cumulative hospitalized days and healthcare costs attributable to rCDI were 1.95 days and $10,580.”In conclusion, the HCRU and economic burden associated with primary and rCDI are quite substantial,” the authors write. “Better prevention and treatment of CDI, especially rCDI, are needed.”Jan 19 Clin Infect Dis studylast_img read more

UCL Review: Sevilla Dump Out ‘Sorry’ Manchester United To End A 60-Year Wait; Roma…

first_imgSevilla have qualified for the quarterfinals of the UEFA Champions League (UCL) after they surprisingly defeated Manchester United 2-1 on aggregate in their last 16 tie.Substitute Wissem Ben Yedder was the hero for the Spanish side as he scored two goals in four minutes just after coming on to hand his side a 2-0 lead before Belgian striker Romelu Lukaku pulled one back for the hosts in the final ten minutes.Vicenzo Montella’s men thereafter held on for the 2-1 scoreline at Old Trafford thus securing a 2-1 aggregate win over the Red Devils after a goalless affair in the first leg 20 days ago.With the win, Sevilla secure a last eight berth for the first time in 60 years (since 1958).Italian side AS Roma are also through to the quarterfinals after star striker Edin Dzeko scored very early in the second half to give the capital club a 1-0 win over 10-man Shakthar Donetsk who had Ivan Ordets sent off in the second half.Roma secure passage into the last eight on away goals having lost 2-1 in the away leg in Ukraine three weeks ago.Relatedlast_img read more

Health hub on the way

first_imgBy ANEEKA SIMONIS PAKENHAM’S health super centre is one step closer to beginning construction. Monash Health has appointed a builder…[To read the rest of this story Subscribe or Login to the Gazette Access Pass] Thanks for reading the Pakenham Berwick Gazette. Subscribe or Login to read the rest of this content with the Gazette Digital Access Pass subscription.last_img

Selkirk Saints ink pair to 2018-19 roster

first_imgShatford will start his post-secondary pathway in the Millwright/Machinist Program on Nelson’s Silver King Campus and then plans to enrol in the School of Business Administration for his second year at Selkirk College.“I hope to help the Saints get the BCIHL Championship back,” says Shatford. “I play a high energy, physical game and love to win. I can’t wait to suit up for the Saints this season and next.”Last season, Freed played in the Greater Metro Junior A Hockey League (GMHL) for the Temiscaming Titans where he led his team in scoring with 44 goals and 56 assists in only 35 games.“Rylan is a player that we feel has an exceptional upside, he brings more than 180 games of junior A experience and with that a deep knowledge of what it takes to succeed,” says Heaven. “We expect Rylan to be able to help bolster the Saints offense, while increasing the level of compete within our group.”Freed will be begin his post-secondary in the School of Business Administration on the Castlegar Campus.“The reason I chose Selkirk College was mainly because the college was very welcoming, they were understanding with the program I was interested in taking and were interested in helping me with my future,” says Freed, who plays centre. “On the ice, I look forward to bringing some speed and offense along with a good two-way game because everything starts from your defensive zone.”The Saints made it to the BCIHL championship series this past spring, but were defeated by the Trinity Western University Spartans. Winners of four championships in a row between 2013 and 2016, the team is looking to return the provincial title to the West Kootenay this coming season. The Saints training camp starts in September. The Selkirk College Saints will welcome a pair of proven offensive threats when the British Columbia Intercollegiate Hockey League (BCIHL) season begins in September.With the departure of offensive powerhouse Dallas Calvin, a priority on head coach Brent Heaven’s off-season to-do list is to find players to help fill the gap for the 2018-2019 season. The Saints’ coach will be looking to Nova Scotia native Josh Shatford and Saskatchewan native Rylan Freed to help carry the offensive weight in the upcoming season.“Josh is a highly skilled player with over 250 games of experience between junior A and the major junior level,” says Heaven. “He plays with an edge and has a strong hockey IQ, which helps his offensive flare. We feel that he will be able to step in and contribute at both ends of the ice immediately for the Saints.”Last season, Shatford played in the Sask West Hockey League (SWHL) where he scored 26 goals in 19 games, added 21 assists and compiled 95 penalty minutes.“I chose Selkirk College because I heard great things from guys who have played there,” says Shatford, who also spent time in the Quebec Major Junior Hockey League (QMJHL). “Selkirk College has a great and storied hockey program, and can offer me the training I was looking for in an awesome environment.”last_img read more

Christian Eriksen strikes in stoppage time as Tottenham snatch late win

first_imgCHRISTIAN ERIKSEN kept Tottenham title hopes alive with a stoppage-time winner.The jubilation of the draw in Barcelona which sealed qualification for the last 16 of the Champions League was disappearing in a damp squib of a performance against dogged Burnley.6 Christian Eriksen scores the dramatic late winner for SpursCredit: Getty – Contributor6 Eriksen arrives to fire Spurs to victory and shatter BurnleyCredit: Reuters6 The midfielder is mobbed by Spurs team-mates after the dramatic late winnerCredit: ReutersErik Lamela, Son Heung-Min and Dele Alli had all missed late chances to snatch a winner.But second-half substitute Eriksen came up with the good again to keep Spurs on the tails of Liverpool and Manchester City.Until the late winner, the only plus point for the home team looked like being a decent first start in the senior team for Oliver Skipp, 18, who played in defensive midfield as Mauricio Pochettino shuffled his team to make up for FOUR centre backs being out with injury.Lucas Moura and Lamela failed to convert decent opportunities in the first half , the latter when Joe Hart made a good smothering save.6 Danny Rose bites the dust under a Phil Bardsley challenge in a gritty match at WembleyCredit: PA:Press AssociationMost read in footballBRO MESSAGEBobby Charlton’s touching tribute to Jack revealed as he misses funeral serviceFRESH OUTFITMicah Richards pokes fun at Roy Keane backstage at Sky Sports studiosFALL OF TROYDeeney calls Sky reporter ‘cheeky b******’ after he asks about retirementSHOTS FIREDDenis Irwin’s son trolls Liverpool fans with savage Steven Gerrard tweetPicturedC’MON THE LADSRamos’ becomes dad again as wife gives birth to FOURTH son Maximo AdrianoVideoROY MEANKeane says ‘that’s why they never win anything’ as Villa celebrate staying upHarry Kane had a good shout for a penalty turned down as Burnley frustrated the home team with their compact shape and commitment.Ashley Barnes thought he had given the visitors a shock lead just after the break, only for a combination of Toby Alderweireld and Kane to block his acrobatic effort.From then on, Spurs enjoyed most of the possession and territory yet found it hard to create clear-cut chances.Pochettino sent on Christian Eriksen with 25 minutes left but the chances were falling to others.Is this Danny Rose cross for Tottenham the worst of all time?6 Oliver Skipp made his full debut in the centre of the Tottenham midfieldCredit: AFP or licensors6 Robbie Brady attempts an overhead kick as Burnley searched for the breakthroughCredit: PA:Empics SportIn the 75th minute the ball came to Lamela just outside the six-yard box but Hart made a fine one-armed saved to keep out the low shot.Then Son dragged a shot wide from even close range with five minutes left.When Dele was unable to force in a Son cross at the far post, it seemed Burnley, who had Robbie Brady and Phil Bardsley booked for timewasting, would hold on for a point.But in the final minute, Dele and Kane combined to tee up Eriksen to complete a fine week for Tottenham.Watch all the Premier League action from Saturday 15th Decemberlast_img read more

First Look: Facebook’s New Timeline Design

first_imgScrolling Through Your PastWhen you start to navigate your profile in Timeline, you begin to see the power this has to bring back memories of past times. I only joined Facebook in 2007, as I wasn’t a U.S. college student. But even scrolling back just 4 years to 2007, I found myself reminiscing about the friends I added back then, photos of me (beardless!), the groups I joined, events I went to, and more. It’s worth noting that this will become even more powerful the more information about your life that you put on Facebook. As Marshall opined earlier today, over time your Facebook Timeline will become a digital equivalent of you. Conclusion: Big Vision From Facebook!In this post I’ve just covered the new Timeline profile. There is a lot more to explore in the upcoming new Facebook, including “social apps” that allow you to post about what music you’re listening to among other things (this appears to be invite only at this stage). The Timeline profile alone though is seriously impressive. It’s colorful, easily navigable and has the potential to become a wonderful memory bank for you – plus of course your family and friends. There are implications to that, including that you’re going to have to assess for yourself just how much information about your life you want to show in Facebook. Also you’ll need to decide how much effort you want to put in to update your Facebook with “life events” – for past events and as you start to add new ones.Overall, I think this is a big play by Facebook for future generations of Facebook users. Imagine starting from scratch with this Timeline design when you’re a teenager and over the years building up a life story about yourself within Facebook. That’s the big picture to this new Facebook Timeline. It’s a wide-reaching and strong vision.While I anticipate that a lot of current Facebook users won’t want to go through the hassle of updating their past activity, people will adjust over time and begin to add life events, share media and so on. Future Facebook users will just dive in head first.The Facebook Timeline will go live for all in the coming weeks. In the meantime, let us know what you think of the new design in the comments! Facebook is Becoming Less Personal and More Pro… Guide to Performing Bulk Email Verification When you add a life event, it’s as simple as filling in a few fields. Related Posts A Comprehensive Guide to a Content Audit richard macmanus Life Events: New Forms of Status UpdatesA key feature in the new Timeline profile is the ability to define different types of “life events.” The status update field now has 5 different icons: Work and Education, Family and Relationships, Living, Health and Wellness, Milestones and Experiences. The Dos and Don’ts of Brand Awareness Videos Tags:#Facebook#social networks#web One thing I’m really liking about this new design is how it encourages you to add photos, which makes your Facebook profile much more colorful. If you click one, for example ‘Living’, you are given a list of further options. The biggest announcement at Facebook’s f8 event in San Francisco today was a radical new profile design. Called Timeline, the new design turns your profile into a colorful, easily searchable timeline of your entire life – at least the parts of it on Facebook. The Timeline won’t go live until a few weeks, but you can set it up as a developer preview by following these instructions. This is a “Developer Release” version of Timeline, so it may be a little buggy.Here is a first look at Facebook’s Timeline, using my own Facebook account.Initial Set-upThe first thing you’re prompted to do is add a cover photo to your Timeline profile. I chose a photo from a past ReadWriteWeb Summit (see above). Also note the timeline navigation bar to the right of the cover photo. As you scroll down your profile page, you will see little dots in a central vertical timeline. Click the dots and it pops up with the update from that particular time (see below). Another key difference with this profile design is that your updates are segmented into boxes.You can control which things are emphasized in your profile by starring them. In the following example, I starred a photo I took at a local festival. This changed it from a half-page status update into a widescreen one. View ActivityFinally, it’s worth highlighting the ‘View Activity’ link, which is prominently displayed on your new profile. This is private to you. It lists all of your recent activity, allowing you to update privacy settings and more.last_img read more

Robert Downey Jr debuts first image of daughter Avri

first_imgAvengers star Robert Downey Jr shared the first ever image of her baby daughter Avri.During his appearance on the “Late Show with David Letterman”, the proud father was all smiles as the photo of his cute little girl was projected on the show’s giant screen, reported Ace Showbiz.Five-month-old Avri could be seen on the snapshot having wide blue eyes. She was spotted sporting yellow hoodie as she stared into the camera.Daughter of Robert Downey Jr Avri. (Pics: CBS)During the interview, the 50-year-old actor also told host David Letterman about his recent birthday celebration that took place in an airplane hangar.The actor has two-year-old son Exton with his producer wife of nine years. He also has a 21-year-old son, Indio, from a previous marriage.The actor had earlier admitted he can’t stop taking pictures of Avri.He had written: “After 9 months of intensive development, Team Downey is pleased to announce our 2014 fall/winter project.””Principal photography commenced 11-14 and will continue until she says, ‘Dad! You are embarrassing me…I’m 30, this has gotta stop.'”Robert Downey JrRobert previously confessed he was nervous about raising a daughter.He said: “I’ve never had a daughter before, so I don’t know what really prepares a dad. I’m asking around. But I did my part and now I’m just going to show up and do what I’m told.”(With input from agencies)last_img read more

Caslick Keen To Learn From The Best

first_imgAnd later this week she will run out in the green and gold uniform of the Australian Women’s Open team when they battle it out against New Zealand in the 2012 Trans Tasman Test Series in Mudgee, New South Wales. The Brisbane school student, who turned 17 last month, becomes one of the youngest players to ever represent Australia at an Open’s level, while teammate Ashleigh Quinlan, who turned 17 late last year, also joins her in the team. While Caslick didn’t expect to be making the team so early in her career, she is looking forward to making her mark on the series when it starts on Thursday. “I was sort of a bit shocked but yeah I’m really excited, I can’t wait,” Caslick said. Caslick started playing Touch Football as an 11-year-old, and it didn’t take long for her to impress on the field, making her first Queensland team that year. While it’s been a big 12 months for the 17-year-old, which included helping her side, the Brisbane City Cobras win the 2012 National Touch League Women’s Open title, she is keen to use this week’s experience to learn as much as she can from some of her Touch Football idols, and she says she has already learnt plenty along the way.   “I’d already played with Woodsy (Kelly Woods) and Chez (Emilee Cherry) before but playing with Peta (Rogerson) and Louise Winchester and KJ (Kristy Judd), they just taught me so much and they were so encouraging, just learning from all of them, they all have little things that help so much.”“I think I’m just going to learn so much from the older girls and that’s what I’m looking forward to the most, I think it will be fun in general,” she said. Caslick credits Australian Women’s Open coach, Peter Bell as one of the biggest influences on her Touch Football career to date and says that having him as her coach at the highest level is making her feel more comfortable in the lead up to the series. Representing Australia at the Open’s level at such a young age doesn’t seem to faze Caslick, who after representing the Australian 18’s Girls team last year made it her next goal to make the Women’s Open team. “I haven’t really thought about how young I actually am, I’m honoured to have had so much help… everyone has helped me so much.”Stay tuned to the website to meet the team’s other 17-year-old, Ashleigh Quinlan, in the coming days. There are plenty of ways to keep in touch with the 2012 Trans Tasman Series, which will be held at Mudgee’s Glen Willow Regional Sporting Complex from Thursday, 26 April to Saturday, 28 April 2012, including in the following ways:Websites:www.austouch.com.auwww.transtasman.mytouchfooty.com Facebook – www.facebook.com/touchfootballaustraliaTwitter – www.twitter.com/touchfootyaus (be sure to use the hashtag #transtasman2012 in your tweets)YouTube – www.youtube.com/touchfootballauslast_img read more

a month agoLiverpool fullback Robertson to miss Napoli clash

first_imgLiverpool fullback Robertson to miss Napoli clashby Paul Vegasa month agoSend to a friendShare the loveAndrew Robertson is set to miss Liverpool’s Champions League clash with Napoli.Robertson is a doubt for Liverpool’s Champions League clash against Napoli on Tuesday night.Jurgen Klopp told Liverpool’s official website: “Robbo didn’t train today and we have to see. “It is not a major thing, it was more precautionary today, but it is not 100 per cent sure [he will be available].”We will have to test it tomorrow and then we will see.”Initially it was reported that Robertson had been cleared as he had travelled with the squad but he missed training on Monday morning with a slight knock. The Reds sold Alberto Moreno in the summer and did not sign a back-up left-back. This means James Milner or Joe Gomez is likely to play in defence if Robertson can not overcome his knock in time. About the authorPaul VegasShare the loveHave your saylast_img read more

Port of Long Beach to Continue Modernization Works

first_imgzoom The Long Beach Board of Harbor Commissioners has approved a USD 748 million budget for the Port of Long Beach in the next fiscal year, with more than 60 percent set aside to continue its modernization program.The budget will be presented to the Long Beach City Council for approval. For the fiscal year starting October 1, 2017, the port plans to spend USD 457 million on capital projects, a part of this decade’s USD 4 billion program to increase efficiency by upgrading terminals, waterways, bridges, rail lines, marine safety and other vital infrastructure.“This spending blueprint advances the nation’s largest seaport modernization program and our practice of investing revenue back into our harbor, a leading economic engine for this region, the state and the nation,” Lori Ann Guzmán, Harbor Commission President, said.“The budget reflects this Port’s fiscally prudent, results-driven approach to budgeting and capital improvements,” Guzmán added.The fiscal year 2018 budget projects a 1.8 percent increase in operating revenue over the current year.The budget puts USD 16.4 million into “net position,” designating it for spending in the future, beyond fiscal year 2018.Meanwhile, as part of the approved budget, the port is expected to transfer USD 18.7 million to the city’s Tidelands Operating Fund, which is used for beachfront improvements in Long Beach.Ongoing major capital improvement projects include the Gerald Desmond Bridge replacement and the Middle Harbor redevelopment, a model for green cargo operations and the most advanced facility of its kind in the world, the Port of Long Beach said.Another highlight in the budget includes USD 404,000 in funding for the Port Community Grants Program, approved by the Harbor Commission this year. Over the next 12 to 15 years, funding from the environmental grants program will help offset the impacts of port operations on the surrounding community.last_img read more