Dispatch Releases First New Track In Three Years, ‘Bound By Love’

Ahead of their only 2015 concerts in North America, Dispatch has released their first new track in three years. Titled “Bound By Love”, it’s an upbeat soulful track that arrived just in time for summer. Stream the new tune below:Dispatch will play two “DISPATCH: HUNGER” concerts at Madison Square Garden on July 10th and July 11th, with Dr. Dog and John Butler Trio, respectively. The band will also bring out the Funky Dawgz Brass Band to add some brass to their sound! Don’t miss out… all proceeds go to hunger charities worldwide. read more

Mumford & Sons Welcome Metallica’s Lars Ulrich, Austin High Marching Band At Austin City Limits [Videos]

first_imgOn Sunday night, British folk-rock outfit Mumford & Sons offered up a headlining performance on the final night of weekend two at Austin, TX’s Austin City Limits. The band fronted by Marcus Mumford welcomed Metallica drummer Lars Ulrich and the Austin High Marching Band at different points throughout their set at Zilker Park.Mumford & Sons Announce Inaugural Agora Del Mar 2020 Destination EventMumford & Sons opened up their ACL performance with “42”, which was followed by a mix of fan-favorites and newer material off of the band’s 2018 Delta LP. Towards the middle of their set, the band welcomed the Austin High Marching Band for a special collaborative effort on “The Cave”, which appears on Mumford & Son’s 2009 debut studio album, Sigh No More. According to JamBase, previous collaborations between Mumford & Sons and the Austin High Marching Band took place in 2011 and 2012.Mumford & Sons ft. Austin High Marching Band – “The Cave”[Video: Karma Koma]Following “Ditmas”, “Slip Away”, “Picture You”, and “Darkness Visible”, Marcus Mumford welcomed Ulrich to play drums on the set-closing”The Wolf”, off of 2015’s Wilder Mind. Following a brief break, Mumford & Sons returned to open up their five-song encore on their B stage with “Reminder” and “Awake My Soul”. The band closed out their performance with “Woman”, “I Will Wait”, and “Delta”.Mumford & Sons ft. Lars Ulrich – “The Wolf”[Video: Karma Koma]Head to Mumford & Sons’ website for a full list of the band’s upcoming tour dates, ticketing, and more information.Setlist: Mumford & Sons | Austin City Limits | Austin, TX | 10/13/2019Set: 42, Guiding Light, Little Lion Man, Holland Road, Beloved, Lover of the Light, Tompkins Square Park, Believe, Blind Leading the Blind, Rose of Sharon, The Cave*, Ditmas, Slip Away, Picture You, Darkness Visible, The Wolf^Encore: Reminder, Awake My Soul, Woman, I Will Wait, Delta* w/ Austin High marching band^ w/ Lars Ulrich on drumslast_img read more

Saint Mary’s to host National History Day competiton

first_imgEvery year across the country, students channel their passion for the past through National History Day (NHD), a competition where students present projects through various media.Saint Mary’s is one such site hosting a regional NHD contest on Saturday, where students and professors will judge history projects made by local students ranging from grade to high school.Chair of the history department Bill Svelmoe said the College annually hosts this event.“Saint Mary’s has been hosting this one for many years now,” he said.The local students will present their projects mainly in Spes Unica Hall, where the history department is located.“[The projects] range from posters to papers to theatrical presentations,” history professor David Stefancic said. “And this year I have the pleasure of judging websites.”The competition organizes new themes every year. According to the National History Day website, this year’s theme is “taking a stand in history.”“The topics that I’m looking at are activism: … abolitionists, [the] Declaration of Independence, [the] Civil Rights movement in the ’50s, a young soldier from the Civil War, censorship [and] Tiananmen Square in China,” Stefancic said. “They have to do with social change and revolution.”While many history majors participate, students with any major can volunteer to judge the projects, Svelmoe said.“It’s not just [history] majors and it’s not like you have to really know what’s going on in history,” he said. “Remember, these are often little kids and, as a judge, you can request the age group [to judge].”Junior history and English literature major Brooke Lamb said it is a good opportunity for all Saint Mary’s students. Lamb said judging focuses more on the interview process and understanding what the students have put into their projects.“I think that anyone on campus could judge and [the history department is] willing to have volunteers,” Lamb said.The judges work in groups to examine and compare presentations.“You don’t judge anything by yourself — there’s usually three of you, at least, that are working together,” Svelmoe said. “It’s not all on you to crush some child’s dreams.”Judges score the students on their visuals and presentation and give feedback on the projects.“At the end of the day, you get together and you rank the presentations,” Svelmoe said. “The top ones advance [but] you try to say something encouraging about all of them.”Stefanic said student judging is a good way to see what young students are doing at lower levels.“You have a chance to see what’s going on there, particularly if you’re considering going onto teaching in grade school or junior high,” Stefancic said. “Also, you have a chance to meet some really cool kids.”The day also introduces local students to the College and Stefancic said the competition is a hidden recruiting tool for the students participating.“There have been instances where the students who were taking part of this met us and then decided to come to Saint Mary’s,” he said.Tags: Bill Svelmoe, David Stefanic, National History Day, SMC history departmentlast_img read more

VEEP partners with Vermont Gas to offer workshop on weatherization

first_imgVermont Business Magazine The Vermont Energy Education Program (VEEP) has partnered with Vermont Gas to update its Button Up in-class workshop, giving middle and high school students a hands-on way to learn about thermal energy by exploring the effects of home weatherization. For students living in towns served by Vermont Gas, VEEP educators will bring the workshop to their classrooms at no cost. The partnership is all about increasing energy literacy among young Vermonters and increasing awareness of the importance of energy efficiency.The workshop was partially funded by Vermont Gas, which provides gas to over 50,000 customers in Chittenden and Franklin counties.  The company expects to soon serve families and businesses in Addison County.“VEEP is delighted to see Vermont Gas expand its efforts to include helping its young customers understand how to reduce their use of heating fuel and decrease the amount of money spent on energy,” said Cara Robechek, VEEP’s executive director.“We believe the cleanest and most affordable energy is the one we don’t use, that’s why we work so hard to help our customers reduce their energy needs through our award-winning efficiency programs,” said Don Rendall, President and CEO of Vermont Gas. “Working with the folks at VEEP to teach young Vermonters how to reduce their energy consumption and become more efficient is an important part of our work to build a cleaner energy future.”In the two-hour workshop, students are asked to consider how they can use less energy to heat their home while still keeping it at a comfortable temperature. They explore different insulation and air-sealing materials as well as data from model houses. High school students even take on a home heating challenge where they play the role of new homeowners, researching and “purchasing” weatherization improvements.“I love that there is a real-life application to the core idea of thermal energy,” said Jess Angell, VEEP director of curriculum and education. “I also love that it is an application that is meaningful to the current energy and climate issues in Vermont with an emphasis on ways students can make a difference.”In addition to updating the workshop, the staff at VEEP have created a workshop extension for grades 6–8, challenging middle school students to design, construct, and test a model house with the goal of making it as efficient to heat as possible. VEEP educators can support teachers in leading this extension or other lessons on energy to fit with their curriculum.For more information on VEEP’s statewide in-class workshops, curricula, professional development for teachers, and other hands-on energy education programs, visit veep.org(link is external). You can also contact Cara Robechek at 802-552-VNRG or e-mail [email protected](link sends e-mail) to schedule a local VEEP educator for your school.VEEPThe Vermont Energy Education Program’s mission is to promote energy literacy — a deep understanding of what energy is and how to use it efficiently — in schools and communities, to enable energy usage choices that will result in a sustainable and vital economy and a healthy environment.About Vermont GasVermont Gas Systems is a leader in energy efficiency and innovation, offering a clean, safe, affordable choice for over 50,000 homes, businesses, and institutions in Franklin and Chittenden counties. The company plays an important role in Vermont’s clean energy future by displacing higher-emitting fuels and with its award-winning energy efficiency programs. For more information about Vermont Gas visit www.VermontGas.com(link is external).Source: Vermont Gas. 8.30.2016last_img read more

New Time to Tri Virtual Triathlon for newbies and experienced triathletes…

first_img Related USA Triathlon (USAT) has unveiled plans for what is being billed as ‘the world’s first entirely online swim, bike and run event’, the Time to Tri Virtual Triathlon, which will run from Friday, November 1, through Sunday, December 1.The online challenge, housed at virtual-tri.com from November 1, gives aspiring triathletes the chance to experience the sport for the first time in an approachable format. At the same time, it offers experienced multisport athletes a virtual racing and training opportunity.Registration is free, and participants who add-on a US$35 donation to the USA Triathlon Foundation will receive a Virtual Triathlon T-shirt and finisher’s medal.All finishers, regardless of whether they select the USA Triathlon Foundation upgrade, will receive a US$20 gift card to roka.com upon completion of the challenge.Registration is currently open at virtual-tri.com. Athletes can sign up prior to the start of the challenge or at any point during the four-week period.The event is a component of Time to Tri, an industry-wide initiative within the triathlon industry to grow the sport by proactively recruiting and supporting athletes as they train for and complete their first race. The three-year initiative, a strategic joint effort between USA Triathlon and IRONMAN, was unveiled in early 2018.“In order to grow our triathlon community, we need to meet prospective triathletes at the very start of their journey and make their introduction to the sport as seamless as possible,” said Rocky Harris, USA Triathlon CEO. “The virtual triathlon does exactly that – enabling participants to swim, bike and run on their own time and in whatever format works best for them. If we can create a positive first experience, we know we will inspire many athletes to sign up for a local race as the next step.”During the four-week-long event, participants will be challenged to complete the swim, bike and run distances for a sprint- or Olympic-distance triathlon. Athletes can complete all three disciplines on the same day, or complete one discipline at a time over the course of several days or weeks.Swim, bike and run workouts can be synced to the platform automatically via most GPS-enabled workout devices, smartphone apps and smartwatches – including Garmin, Apple Watch, FitBit, Misfit, Polar, Strava, Suunto, Google Fit, RunKeeper, Apple Health and MapMyFitness. Manual uploads are also permitted.First-time triathletes are encouraged to complete the sprint-distance triathlon, which is focused on participation rather than competition and consists of a 500m swim, 12.5 mile bike and 3.1 mile run. The Olympic-distance event consists of a 1,500m swim, 25 mile bike and 6.2 mile run, and will feature live leaderboards and rankings of participants nationwide throughout the month.The Olympic-distance event will also include a club competition, with scoring based on total distance completed. Athletes will be able to sign up under their club’s name upon registration.Athletes can upload workouts to the platform, powered by FitRankings, at any time over the four weeks. Participants will be listed as finishers as long as they complete their selected race distance by the end of the challenge on December 1. Workouts may be completed outdoors or indoors: pool swims, spin bikes and stationary bikes, bike trainers and treadmills are all acceptable.“FitRankings strives to be a leader in virtual racing technology, and we are excited to partner with USA Triathlon to create new virtual racing opportunities for USA Triathlon members and the larger triathlon community,” said Patrick Hitchins, CEO and Founder of FitRankings.“We know the triathlon community is on the cutting edge of technology using many different wearables and apps to train and race, so this partnership is a natural fit.”teamusa.org/USA-Triathlon/Virtual-Triathlonwww.usatriathlonfoundation.orglast_img read more

Four stages of a compliance audit

first_imgA robust internal compliance audit program limits exposure to costly litigationby: David A. ReedA compliance audit is simply a comprehensive review of how your credit union adheres to regulatory requirements and related policies the board adopts.The compliance audit program is an annual review with a defined scope that reviews policies, procedures, training materials, staffing, forms, and work samples. It concludes with a report of significant findings, conclusions, and recommendations.The process certainly should include reporting back to the board or a designated committee.A successful compliance audit program consists of four stages:1. PlanningThe planning stage is perhaps the most important as it creates the roadmap for the entire audit process. The schedule and coverage of the audit program depends on the fuzzy, yet often-used, phrase, “size and complexity” of your operation.You must customize your program based on assets, products, and delivery methods. A detailed review of prior audits, examinations, and current risk assessment will assist you in determining the priority of your individual audits.The audit scope should include previous audit and examination findings, requirements, new product channels, and self-identified high-risk areas.Senior management must impress upon departments the importance of cooperation and timeliness. The staff member charged with conducting the audit needs to coordinate among all operational areas and present an item-request list to each audited area with sufficient time for review and production. continue reading » 2SHARESShareShareSharePrintMailGooglePinterestDiggRedditStumbleuponDeliciousBufferTumblrlast_img read more

Liberty Property Trust Acquires One Of Valley’s Largest Vacant Warehouses, 73 Acres Of Land

first_imgLiberty Property Trust finalized two acquisitions in the past few days, purchasing a nearly completed 593,600 SF warehouse — Estrella Logistics Center; and in a separate deal, bought 73 acres of land at Buckeye Logistics Center West.Both are in the highly desirable Southwest Phoenix Industrial submarket.“The Southwest Phoenix industrial submarket is poised for explosive growth, and these acquisitions give us two things: the largest contiguous cross-dock industrial space in the market and land on which to develop even more,” said John DiVall, senior vice president & city manager, Liberty Property Trust. “We are very pleased to have two great opportunities by which to expand our presence in this part of the market.”The industrial building is at 563 S. 63rd Ave. and was purchased from Seefried Properties and USAA. Marc Hertzberg and Anthony Lydon of Jones Lang LaSalle represented the seller and Bo Mills and Mark Detmer of Jones Lang LaSalle represented Liberty Property Trust.The building will be rebranded as “Liberty Logistics Center I” and marketed to distribution center users who want to expand in or locate to Phoenix.“We are currently monitoring more than 10 MSF of industrial users who seek space solutions greater than 100,000 SF,” said Anthony Lydon who, with partner Marc Hertzberg, will retain the leasing assignment on the building.“Southwest Phoenix provides the perfect supply chain nexus for the near-shoring of Mexico and far-shoring of China/India through the ports of Los Angeles and Long Beach. Liberty Logistics Center I will provide the modern amenities that the logistics industry mandates for today’s multi-channel fulfillment needs.”The sustainable building, designed to meet LEED certification, is a state-of-the-art cross-dock facility that features 32-foot clear heights, a fully gated concrete truck court, 7 points of ingress and egress, R-19 insulation and skylights on 2% of the roof.“This is a building we would have built ourselves,” DiVall said. “The high quality and sustainable features are very similar to our own products. It is meant for one or two large users. There’s nothing else in the market like it.”The land purchase is 1.5 miles west of the new building at 71st Ave. and Buckeye Rd. Acquired from The Alter Group, the site is pre-planned to offer more than 1.4 MSF of industrial space across three proposed buildings.It will also be rebranded, as “Liberty Logistics Center II.” Rob Martensen of Colliers International represented the seller in the transaction.“Once we reach about 50% occupancy in Liberty Logistics Center I, we plan to begin work on the first building at Liberty Logistics Center II,” DiVall added.Liberty currently has a presence in the Southwest Phoenix Industrial Submarket, including the 403,321 SF Liberty Tolleson Center at 8591–8601 W. Washington in Tolleson; 227,259 SF at 8313 W. Pierce in Tolleson, and 112 acres of developable land in Goodyear.In total, the company’s Arizona portfolio now includes 2.658 MSF of industrial and office space and 204 acres of developable land in Phoenix, Southwest Phoenix, Tolleson and Goodyear.last_img read more

FlixBus officially entered Croatia

first_imgFollowing the announcement of a major expansion and expansion to Central and Eastern Europe, the international bus operator and mobile brand FlixBus, opened its doors to Croatian passengers. With the opening of the regional branch of FlixBus in Zagreb, Croatia has become the main hub of Central and Eastern Europe.The first Croatian partners to recognize this successful business model, Brioni Pula, Vincek transport, Slavonia Bus and transport Knežević will green the roads from the south of Croatia, along the entire coast and Istria, all the way to Zagreb and Eastern Croatia.˝With its business model, FlixBus has managed to attract millions of passengers across Europe (we already number almost 35 million) and has created thousands of new jobs in the industry and strengthened the business of regional bus carriers. This is exactly what we wanted to provide to Croatian passengers and domestic bus carriers, so we started this project at the end of last year, and already in January 2016, after conquering the market all the way to England, Spain and Scandinavia, we announced expansion in Central and Eastern Europe.˝ said Mr. Dean Chebohin, Business Development Director for CEE.The success of the FlixBus business model confirms that innovation and entrepreneurial spirit combined with the experience and quality of a traditional bus company make this European FlixBus network of bus lines strong and bring a whole new form of business to passenger bus transport. ”With regional partners and an ultra-modern fleet of luxury buses, we can really rely on generations of experience in bus transport in Croatia. Combining entrepreneurial spirit and innovative technology with traditional small and medium-sized enterprises, we have established a completely new form of transport. We just made the buses a cool way to travel.˝ pointed out André Schwämmlein, one of the three founders of FlixBus.By coming to the Croatian market, FlixBus sets new standards and provides more space between seats, socket, free internet, possibility to buy drinks and snacks on the bus, free luggage and the possibility of cancellation or change of reservation up to 15 minutes before departure free of charge. This high level of service and an excellent wide network of bus lines throughout Europe, FlixBus provides at dynamic prices that are available to everyone and range from 9 € / 69kn, depending on how early you can plan your trip.In the fall, further connections were announced with other neighboring countries, ie with Switzerland, the Czech Republic, Slovakia and Bosnia and Herzegovina, and domestic lines will be strengthened in order to make the interconnection of cities in Croatia as high quality as possible. FlixBus introduced new travel standards on the Croatian market, more acceptable travel prices and open access to the largest European network of autobunish lines.last_img read more

Parkinson’s disease research puts designer dopamine neurons within reach

first_imgShare on Facebook A cellular ‘gatekeeper’The new research, published Dec. 7 in Nature Communications, revolves around their discovery that p53, a transcription factor protein, acts as a gatekeeper protein.“We found that p53 tries to maintain the status quo in a cell, it guards against changes from one cell type to another,” explained Jian Feng, PhD, senior author and professor in the Department of Physiology and Biophysics in the Jacobs School of Medicine and Biomedical Sciences at UB. “We found that p53 acts as a kind of gatekeeper protein to prevent conversion into another type of cell. Once we lowered the expression of p53, then things got interesting: We were able to reprogram the fibroblasts into neurons much more easily.”The advance has importance to basic cell biology, Feng said. “This is a generic way for us to change cells from one type to another,” he said. “It proves that we can treat the cell as a software system, when we remove the barriers to change. If we can identify transcription factor combinations that control which genes are turned on and off, we can change how the genome is being read. We might be able to play with the system more quickly and we might be able to generate tissues similar to those in the body, even brain tissue.“People like to think that things proceed in a hierarchical way, that we start from a single cell and develop into an adult with about 40 trillion cells, but our results prove that there is no hierarchy,” he continued. “All our cells have the same source code as our first cell; this code is read differently to generate all types of cells that make up the body.”Generating new dopamine neurons via cellular conversionTiming was key to their success. “We found that the point in the cell cycle just before the cell tries to sense its environment to ensure that all is ready for duplicating the genome, is the prime time when the cell is receptive to change,” said Feng.By lowering the genomic gatekeeper p53 at the right time of cell cycle, they could easily turn the skin cells into dopamine neurons, with transcription factor combinations discovered in previous studies. These manipulations turn on the expression of Tet1, a DNA modification enzyme that changes how the genome is read.“Our method is faster and much more efficient than previously developed ones,” said Feng. “The best previous method could take two weeks to produce 5 percent dopamine neurons. With ours, we got 60 percent dopamine neurons in ten days.”The researchers have done multiple experiments to prove that these neurons are functional mid-brain dopaminergic neurons, the type lost in Parkinson’s disease.The finding enables researchers to generate patient-specific neurons in a dish that could then be transplanted into the brain to repair the faulty neurons. It can also be used to efficiently screen new treatments for Parkinson’s disease. For decades, the elusive holy grail in Parkinson’s disease research has been finding a way to repair faulty dopamine neurons and put them back into patients, where they will start producing dopamine again. Researchers have used fetal material, which is difficult to obtain and of variable quality. Embryonic stem cells represented a tremendous innovation, but making dopamine neurons from stem cells is a long process with a low yield.These issues have driven researchers to try to develop ways to turn cells that are easy to obtain, such as skin cells, into dopamine neurons, which are normally hidden in the brain. But here, too, it has been difficult to obtain sufficient quantities of neurons.Now, Parkinson’s disease researchers at the Jacobs School of Medicine and Biomedical Sciences at the University at Buffalo have developed a way to ramp up the conversion of skin cells into dopamine neurons. They have identified – and found a way to overcome -a key obstacle to such cellular conversions. At the same time, the researchers say the finding has profound implications for changing the way scientists work with all cells. Share on Twitter Pinterestcenter_img LinkedIn Email Sharelast_img read more

China reports 4 more H7N9 infections

first_imgApr 2, 2013 (CIDRAP News) – Chinese health officials today reported that the H7N9 influenza virus has been detected in four more people, all in critical condition, raising the number of patients infected with the new strain to seven.All of the patients are from Jiangsu province, an area on China’s eastern coast that borders the city of Shanghai and Anhui province, the two areas that reported the first three H7N9 cases, which included the deaths of two men from Shanghai.A statement today from the Jiangsu Province Health Department, identified and translated this morning by the Avian Flu Diary blog, said all four patients—three women and a man—are in critical condition at hospitals in Nanjing, Wujiang, and Wuxi.One is a 45-year-old woman from Jiangning district who worked as a poultry slaughterer. She became ill with a fever, body aches, and other symptoms on Mar 19 and was hospitalized on Mar 27. The second patient, a 48-year-old woman from the city of Suqian who is a sheet metal worker, got sick with similar symptoms on Mar 19 and was hospitalized on Mar 30.The man who was infected is an 83-year-old resident of Suzhou Wujiang district who came down with a fever and respiratory symptoms on Mar 20 and was hospitalized on Mar 29. The fourth patient is a 32-year-old woman from the city of Wuxi who is unemployed. She started having a cough, fever, and other symptoms on Mar 21 and was hospitalized on Mar 28.The Jiangsu Provincial Center for Disease Control and Prevention detected the H7N9 virus in samples from the patients, and tests at China’s Center for Disease Control and Prevention (China CDC) lab confirmed the results for the first two cases.A statement on the four new cases today from Hong Kong’s Centre for Health Protection (CHP) said China’s National Health and Family Planning Commission has verified the cases. It added that no epidemiologic links have been found between the four patients and so far no other H7N9 infections have been identified in 167 of their close contacts.The CHP advised travelers, especially those returning from Shanghai, Anhui province, and Jiangsu province, who have respiratory symptoms to wear face masks, seek medical attention, and share their travel histories with their doctors. It also urged healthcare workers to take extra precautions with travelers who may have had contact with poultry in the three areas.Yesterday Chinese health officials said the source of the infections is probably poultry. The H7N9 virus has previously infected only birds, though other H7 subtypes have been known to infect humans, typically causing conjunctivitis and mild respiratory symptoms.In another statement today, the CHP said it activated Hong Kong’s pandemic alert response level, which triggers certain surveillance and control measures. The alert level is the lowest response category. The next level is serious, and the highest is the emergency level.The city of Shanghai has activated its emergency response plan, based on two recent infections and deaths from H7N9 in the area, and health officials in Beijing have stepped up their surveillance for hospitalized cases of avian flu and pneumonia from unknown cases, The Standard, an English-language daily newspaper in Hong Kong, reported today.The World Health Organization (WHO) today published a frequently-asked-questions resource about H7N9 on its Web page, which emphasized that so far health officials have found no evidence of human-to-human spread, though investigators are exploring all possible sources.”The risk associated with A (H7N9) avian influenza virus to the general population in China and beyond is being investigated and will be shared to the public when information becomes available,” the WHO said.Les Sims, BVSc, an Australia-based animal health consultant with extensive experience with avian flu in Asia, told CIDRAP News that it’s still too early to draw firm conclusions about the virus, but the history of avian flu viruses in the region and the apparent pattern of the human cases suggest that some or even most of the cases are likely the result of virus transmission from animals to humans.Sims said his early review of genetic evidence in the public domain strongly suggests that the virus originally came from poultry. “In my view, it is only a matter of time before infected poultry will be detected,” he said.Avian infections with low-pathogenicity H7 viruses with a different neuraminidase (N) subtype have been reported in China and the broader region in the recent past, but genetic information suggests that the H7N9 virus marks the first detection of an H7 virus with internal genes from H9N2 viruses.”The evidence I have seen suggests the virus is probably a low pathogenicity strain for poultry and if circulating in poultry would not necessarily be causing severe disease, which has implications for surveillance programs,” Sims said. In contrast, mass poultry deaths in H5N1 are events that signal an imminent threat to humans.Sims said he’s not aware of any poultry vaccination programs for H7 viruses in Asia, except for Pakistan, where vaccines were used to battle a highly pathogenic H7 virus.A news story in Nature today reported other preliminary analyses of H7N9 genetic sequences from virology experts. It reported that Chinese researchers have sequenced isolates from the first three human cases and posted them to the GISAID flu sequence database. Masato Tashiro, MD, PhD, director of the WHO Collaborating Center for Reference and Research on Influenza at Japan’s National Institute of Infectious Diseases in Tokyo, told the journal that his initial assessment is “worrisome,” because the virus shows several features that suggest adaptation to humans.Tashiro said the new virus appears to be a reassortment of three virus strains that infect only birds, according to the report. He told Nature that the N protein is similar to its counterpart in H11N9 viruses found in South Korea, China, and the Czech Republic, and the gene for the hemagglutinin (H) protein—which plays a role in binding to host cells—appears to belong to a Eurasian H7 avian flu group.Researchers said early analysis suggests the virus has developed mutations that allow the H protein to attach to receptors in mammalian airway cells rather than those in poultry airways, according to the Nature report. They also said early studies suggest that H7N9 can infect cells in the lower airways, which can contribute to severe disease but also can limit the spread of the disease through coughing and sneezing.See also:Apr 2 Avian Flu Diary postApr 2 CHP statementApr 2 CHP statement on control measuresApr 2 Standard storyApr 2 WHO H7N9 FAQApr 2 Nature news storyApr 1 CIDRAP News story “China reports three H7N9 infections, two fatal”last_img read more