NIH to double funding for chronic fatigue syndrome, but patient distrust remains

first_img A September protest called Millions Missing displayed shoes belonging to people with chronic fatigue syndrome/myalgic encephalomyelitis. This pair was among scores that lined the sidewalk in front of the Department of Health and Human Services in Washington, D.C. Ever since it was given a name, many researchers and physicians have viewed the malady, which has no Food and Drug Administration–approved treatment and no diagnostic test, as psychosomatic. Then, in 2015, the Institute of Medicine (IOM) dismissed the “misconception” of the disease as psychological in a report informed by a review of more than 9000 articles from 64 years of medical literature. “Remarkably little research funding has been made available to study the etiology, pathophysiology, and effective treatment of this disease, especially given the number of people affected,” the authors noted. CDC estimates that ME/CFS affects more than 1 million Americans, a majority of them women.The IOM report “had an unbelievable effect,” because it validated patients’ experiences—”it told them that they weren’t crazy,” says geneticist Ronald Davis, who directs the Genome Technology Center at Stanford University in Palo Alto, California, and was one of the report’s 15 authors. Davis became a passionate advocate for ME/CFS research and shifted his own studies to the topic after his now 33-year-old son fell ill with ME/CFS in 2008; he is now bedridden. “It also did a lot to NIH and the CDC, who had been ignoring this disease.”Not long after the IOM report was published, NIH issued its own written assessment, concluding that research has neglected many of the biological factors behind ME/CFS and urging more basic science aimed at teasing out the mechanisms of the disease. Collins also announced a “strengthening” of the agency’s ME/CFS effort. He moved oversight of the research out of the agency’s small Office of Research on Women’s Health and into the $1.7 billion National Institute of Neurological Disorders and Stroke (NINDS), and launched an intramural study that began enrolling people late last month. Forty patients who have developed the disease within the last 5 years, after an infection, will be run through a battery of exams at the Clinical Center, the NIH’s research hospital. The assessments, from exercise stress tests to brain magnetic resonance imaging tests, will probe the biological and clinical characteristics of the disease—for which there is not even a broadly agreed-upon definition. For comparison, the study will also include healthy controls and people who have recovered from Lyme disease, which can cause similar symptoms.The disease remains a beggar when it comes to budget.Deborah Waroff, retired Wall Street energy analystSome ME/CFS patients remain skeptical that the NIH moves reflect a genuine commitment to research on the disease. They have criticized what they call the narrow eligibility criteria being used for the Clinical Center study, and they complain that even $15 million scarcely begins to fund the research they say is needed. Critics such as Deborah Waroff, a retired Wall Street energy analyst who fell ill with ME/CFS in 1989, point, for instance, to multiple sclerosis, a similarly chronic, debilitating disease, which affects fewer than half as many Americans, according to one recent estimate. It received about 13 times as much NIH funding in 2016: $98 million. “ME still floats in space, belonging fully to no NIH institute and therefore having de jure claim to no budget,” Waroff says. “The disease remains a beggar when it comes to budget.”Any goodwill won by Whittemore’s appearance in Florida may have evaporated after anger erupted last week when ME/CFS patients learned NIH had invited Edward Shorter, a medical historian at the University of Toronto in Canada, to give a 9 November talk at the agency. Shorter last year called the IOM report affirming the biological basis of ME/CFS “valueless; junk science at its worst.” He traces the disease to a 1970s “brew of toxic beliefs about being tired all the time.”Walter Koroshetz, the director of NINDS, defended the talk, writing in a letter to ME/CFS patients that “inclusion in the scientific conversation is not an endorsement.” In an email to Science, he wrote that Shorter’s talk was not “an official ME/CFS lecture. [An] announcement went out to the contrary. That was recalled. End of story.”Tangible scientific progress on unraveling ME/CFS might be the best medicine to heal the current divisions. A study published in the Proceedings of the National Academy of Sciences in August found depressed blood levels of scores of metabolites in people with the disease compared with healthy controls, suggesting that the disease may push the body into a low-energy state some have compared with hibernation. Scientists and patients are eagerly waiting for the results of a similar study by Lipkin’s team. If replicated, the tantalizing finding could fit with an emerging theory that subpar function by mitochondria, the organelles that provide energy for cells, drives the disease.Hints that the monoclonal antibody rituximab, a drug that destroys antibody-producing B cells, may help some people with ME/CFS have also sparked optimism. ME/CFS patients have a slightly elevated risk of developing B-cell lymphoma, and Norwegian researchers accidentally found that treating a woman who had both conditions with rituximab markedly improved her ME/CFS symptoms. The group went on to do a nonblinded study of the antibody in 29 ME/CFS patients, 18 of whom reported major or moderate improvements in their symptoms. The researchers are now running a larger, double-blind, randomized clinical trial of the drug in 152 patients, planning to evaluate its effectiveness next October.Øystein Fluge, one of the Norwegian trial’s leaders and an oncologist at the University of Bergen’s Haukeland University Hospital in Norway, remains cautious. “Many places on the internet say this is an autoimmune disease. We haven’t said that. We think some features fit, probably, with some autoimmune mechanism. But that’s a hypothesis. We aren’t sure.” Only one thing is sure: After decades of frustration, the mysterious disease remains maddeningly elusive. The most anticipated speaker late last month at an international conference devoted to the mysterious malady commonly known as chronic fatigue syndrome (CFS) was not a scientist with a hot new finding—although there was excitement about new research in the air. Rather, it was a National Institutes of Health (NIH) official bearing good news to a community that has long existed on the margins of the biomedical research establishment. Vicky Whittemore, the agency’s CFS point person in Bethesda, Maryland, delivered on a promise that NIH Director Francis Collins made last year by announcing that NIH spending for research on the poorly understood disease should rise to roughly $15 million in 2017, doubling the estimated $7.6 million handed out in 2016.What’s more, the NIH emissary said to those gathered here, the biomedical agency will in December solicit CFS proposals from outside scientists to establish several collaborative centers for basic and clinical research, and another center to manage their data on the illness. The calls for applications, which will come with dedicated funds from the planned budget increase, are the first of their kind for CFS from the United States’s major medical research funder since 2005. “There is a shifting tide at NIH with regard to ME/CFS,” Whittemore told the conference, incorporating the term that many with the multisystem illness prefer. (ME stands for “myalgic encephalomyelitis,” and the meeting was convened by the International Association for CFS/ME.)center_img Some scientists working on the disease agree. “The fact that there is a budget for it at all means that the agency is taking it seriously. And it’s not coming only out of Francis Collins’s discretionary fund, but from the individual NIH institutes,” says Ian Lipkin, an immunologist at Columbia University, who serves on the Advisory Committee to the Director, Collins’s key group of external advisers. Lipkin is also a principal investigator, with Columbia psychiatrist Mady Hornig, on a $766,000 grant from NIH’s infectious diseases institute to collect samples from hundreds of patients and controls, looking for biomarkers that could be used to diagnose the disease and searching for clues to its causes.Sign up for our daily newsletterGet more great content like this delivered right to you!Country *AfghanistanAland IslandsAlbaniaAlgeriaAndorraAngolaAnguillaAntarcticaAntigua and BarbudaArgentinaArmeniaArubaAustraliaAustriaAzerbaijanBahamasBahrainBangladeshBarbadosBelarusBelgiumBelizeBeninBermudaBhutanBolivia, Plurinational State ofBonaire, Sint Eustatius and SabaBosnia and HerzegovinaBotswanaBouvet IslandBrazilBritish Indian Ocean TerritoryBrunei DarussalamBulgariaBurkina FasoBurundiCambodiaCameroonCanadaCape VerdeCayman IslandsCentral African RepublicChadChileChinaChristmas IslandCocos (Keeling) IslandsColombiaComorosCongoCongo, The Democratic Republic of theCook IslandsCosta RicaCote D’IvoireCroatiaCubaCuraçaoCyprusCzech RepublicDenmarkDjiboutiDominicaDominican RepublicEcuadorEgyptEl SalvadorEquatorial GuineaEritreaEstoniaEthiopiaFalkland Islands (Malvinas)Faroe IslandsFijiFinlandFranceFrench GuianaFrench PolynesiaFrench Southern TerritoriesGabonGambiaGeorgiaGermanyGhanaGibraltarGreeceGreenlandGrenadaGuadeloupeGuatemalaGuernseyGuineaGuinea-BissauGuyanaHaitiHeard Island and Mcdonald IslandsHoly See (Vatican City State)HondurasHong KongHungaryIcelandIndiaIndonesiaIran, Islamic Republic ofIraqIrelandIsle of ManIsraelItalyJamaicaJapanJerseyJordanKazakhstanKenyaKiribatiKorea, Democratic People’s Republic ofKorea, Republic ofKuwaitKyrgyzstanLao People’s Democratic RepublicLatviaLebanonLesothoLiberiaLibyan Arab JamahiriyaLiechtensteinLithuaniaLuxembourgMacaoMacedonia, The Former Yugoslav Republic ofMadagascarMalawiMalaysiaMaldivesMaliMaltaMartiniqueMauritaniaMauritiusMayotteMexicoMoldova, Republic ofMonacoMongoliaMontenegroMontserratMoroccoMozambiqueMyanmarNamibiaNauruNepalNetherlandsNew CaledoniaNew ZealandNicaraguaNigerNigeriaNiueNorfolk IslandNorwayOmanPakistanPalestinianPanamaPapua New GuineaParaguayPeruPhilippinesPitcairnPolandPortugalQatarReunionRomaniaRussian FederationRWANDASaint Barthélemy Saint Helena, Ascension and Tristan da CunhaSaint Kitts and NevisSaint LuciaSaint Martin (French part)Saint Pierre and MiquelonSaint Vincent and the GrenadinesSamoaSan MarinoSao Tome and PrincipeSaudi ArabiaSenegalSerbiaSeychellesSierra LeoneSingaporeSint Maarten (Dutch part)SlovakiaSloveniaSolomon IslandsSomaliaSouth AfricaSouth Georgia and the South Sandwich IslandsSouth SudanSpainSri LankaSudanSurinameSvalbard and Jan MayenSwazilandSwedenSwitzerlandSyrian Arab RepublicTaiwanTajikistanTanzania, United Republic ofThailandTimor-LesteTogoTokelauTongaTrinidad and TobagoTunisiaTurkeyTurkmenistanTurks and Caicos IslandsTuvaluUgandaUkraineUnited Arab EmiratesUnited KingdomUnited StatesUruguayUzbekistanVanuatuVenezuela, Bolivarian Republic ofVietnamVirgin Islands, BritishWallis and FutunaWestern SaharaYemenZambiaZimbabweI also wish to receive emails from AAAS/Science and Science advertisers, including information on products, services and special offers which may include but are not limited to news, careers information & upcoming events.Required fields are included by an asterisk(*)It has been nearly 3 decades since a group of researchers led by the U.S. Centers for Disease Control and Prevention (CDC) coined the term “chronic fatigue syndrome” after an investigation of two outbreaks in the United States. Typified by exhaustion that commonly worsens with physical, mental, or emotional exertion, the condition is also often characterized by short-term memory and concentration problems and profound fatigue that sleep does not relieve. Sufferers may experience widespread muscle and joint pain, immune system problems, headaches, and many other symptoms. The onset of the disease frequently follows an infectious illness.last_img read more

Dominant RCB thrash Kings XI by 10 wickets to live another day,Dominant RCB thrash Kings XI by 10 wickets to live another day

first_imgRoyal Challengers Bangalore batsmen Virat Kohli and Parthiv Patel celebrate their victory during IPL cricket match against Kings XI Punjab, at Holkar Stadium, in Indore on Monday. – PTI × Royal Challengers Bangalore batsmen Virat Kohli and Parthiv Patel celebrate their victory during IPL cricket match against Kings XI Punjab, at Holkar Stadium, in Indore on Monday. – PTI COMMENT Published on May 14, 2018 cricket Royal Challengers Bangalore produced a dominating performance to outclass Kings XI Punjab by 10 wickets and stay afloat in the Indian Premier League here today.After bundling out Kings XI for paltry 88, RCB chased down the target with consummate ease, reaching 92 for no loss in 8.1 overs.Skipper Virat Kohli led from the front with the bat with an unbeaten 48 while Parthiv Patel made unbeaten 40 to help RCB romp home.Kohli struck six fours and two towering sixes during his 28-ball unbeaten knock, while Parthiv’s innings was laced with seven boundaries.While Kings XI slumped to their third successive loss, RCB improved upon their net run rate by sealing the victory in 8.1 overs.RCB now have 10 points from 12 games, same as Kings XI with two games remaining for the both teams.Earlier, Kings XI wilted under pressure as a spirited RCB bundled them out for paltry 88 in the must-win match.Sent into bat, Kings XI innings never got going as they lost wickets like pack of cards from the onset to be bowled out in 15.1 overs.Backed by some good fielding, Umesh Yadav (3/23) came up with an impressive bowling effort up front to destabilise the Kings XI innings.Besides, Yadav, Yuzvendra Chahal (1/6), Colin de Grandhomme (1/8), Moeen Ali (1/13) and Mohammed Siraj (1/17) picked up a wicket each.Aaron Finch top-scored for Kings XI with a 23-ball 26 while KL Rahul made 21 up the order.RCB bowlers were very well complemented by some good outfield catching and three runs outs.Kings XI witnessed a terrible start to their innings after being sent into bat as they lost four wickets with the scoreboard reading just 50 in 6.5 overs.Rahul gave Kings XI a brisk start with a 15-ball 21 in the company of Chris Gayle (18) before Yadav struck twin blows in the fifth over, dismissing both the openers.While Rahul pulled one straight to de Grandhomme a deep square leg, Gayle departed in similar fashion caught by Siraj off another short delivery three balls later.To make matters worse for Kings XI, Karun Nair edged a delivery straight to RCB skipper Kohli at the lone slip in the next over.Wickets kept on tumbling for Kings XI as Marcus Stoinis and Mayank Agarwal too perished when their team needed them the most.While Stoinis was cleaned up by Chahal, Agarwal got a faint edge to a de Grandhomme delivery in the leg side and Patel did the rest behind the stumps.From there on, Kings XI never really recovered and were eventually bundled out for the second lowest total of this years IPL, courtesy some brilliant work at the field by RCB fielders. SHARE SHARE SHARE EMAIL COMMENTSlast_img read more

Shivajians sign Irish midfielder Shane McFaul

first_imgPune, Aug 17 (PTI) DSK Shivajians Football Club today confirmed the signing of former Irish youth international Shane McFaul for a two-year term from 2016 to 2018. The midfielder joins the Pune-based squad after plying his trade in England, United States of America, Finland and Ireland. His playing career so far has been decorated with two major honours with Irish sides. The first being an FAI Cup winner with Sporting Fingal (2009), followed by the League of Ireland Premier Division title with Dublin-based St. Patrick?s Athletic FC in 2013. Other teams Shane has represented during his career include; Notts County and Brighton and Hove Albion FC in England and Finland Premier League sides FC KTP (Kotkan Työväen Palloilijat) and FC Haka. For the record, Shane has been capped numerous times as a youth player at various levels (Under 14 to 21) for the Republic of Ireland. The 30-year-old is a ball-winning midfielder who is equally adept distribution and thus, becomes the second foreign player to be signed by DSK Shivajians FC for the season ahead. Earlier, the club renewed the contract of Spaniard winger Juan Quero. The central midfielder began his career playing local club football in Ireland when he caught the eye of League One side Notts County, and was promoted to the senior squad in 2002 at the age of 16. In 2005, he moved to American side Virginia Beach Mariners, where he spent a year, before signing for UCD Dublin. In January 2008, he signed for Brighton and Hove Albion FC where he made his debut in a 3-0 victory over Crewe Alexandra. Later that year, he sealed a move back to UCD Dublin before moving to Sporting Fingal for the 2009-10 season. He then moved to St. Patrick?s Athletic FC in 2011. In 2012, he had a successful stint in Finland with FC Haka which led to St Patick?s Athletic FC bringing him back for another season. In 2014, he signed for FC KTP in Finland and captained the side in 2016 and played a major part in their promotion-winning campaign, before turning his eyes to the Indian subcontinent and landing a contract at DSK Shivajians FC. PTI BS BSadvertisementlast_img read more

US Open: Petra Kvitova’s relaxed approach pays off

first_imgAfter a five-month injury layoff, Petra Kvitova is taking a relaxed approach to the US Open and it paid off on Sunday when the Czech upset pre-tournament favourite Garbine Muguruza to reach the quarter-finals.Kvitova suffered a career-threatening injury to her left playing hand, when an intruder stabbed her at her home in December but she has been recovering faster than expected.Seeded 13th at Flushing Meadows, Kvitova went through the early rounds without dropping a set but Sunday’s challenge on Arthur Ashe Stadium was supposed to be trickier as she was facing Garbine Muguruza of Spain.She fell 4-1 behind at the start but the two-time Wimbledon champion, who made her comeback at the French Open in May, then won 12 of the 17 remaining games to prevail 7-6(3) 6-3.It was her first win on Arthur Ashe.”I should change my perspective about it. Maybe that’s why I didn’t ever have any expectation to play well here. That’s why probably I am playing more relaxed and more free maybe,” she told a news conference.”I’m always putting a little bit of pressure on myself at Wimbledon because of the titles, I do have them. But I’m trying to find a rhythm at the U.S. Open.”I’m not going on-site the day off. I’m staying by Central Park which is pretty relaxed.”Next up for Kvitova is local favourite Venus Williams, the ninth seed who this season reached her first two grand slam finals since 2009 at the Australian Open and Wimbledon.advertisementBut Kvitova is relishing the challenge.”I think that she’s playing amazing on the majors this year. I mean, she is really playing very, very well on the big stages,” said Kvitova. “She played the final of Wimbledon. She’s a champion. It’s what we all know.”It will be a great match for me to step on Ashe again probably and play there. I mean, we always had tough battles.”I will try my best. I mean, she has a big serve, big server of course. She has something special which the other players doesn’t have. That’s what I will try to play again probably, similar game as today.”last_img read more

New 2019 Win Total Projections For College Football’s Top Programs

first_imgKirk Herbstreit on the set of ESPN's College GameDayNEW YORK, NY – SEPTEMBER 23: GameDay host Kirk Herbstreit is seen during ESPN’s College GameDay show at Times Square on September 23, 2017 in New York City. (Photo by Mike Stobe/Getty Images)College football teams have begun spring practices in preparation for the 2019 season. With just under half-a-year before the new season, sports books are updating their win total projections for the season.On Monday, college football insider Brett McMurphy revealed the most notable win total projections from the BetOnline sports book. Among them are projections from each of the Power Five conferences, along with several notable Group of Five schools.From the SEC, longtime powerhouse Alabama is expected to have the highest total with 11 projected wins. The best total in the SEC East belongs to Georgia with 10.5 wins.In the Big Ten, Ohio State gets the highest win total with 10. Arch-rival Michigan comes in second with 9.5 wins, while powerhouses Penn State and Wisconsin are projected to get 8.5 wins.Win totals via @betonline_agAlabama 11 Auburn 8 Boise 8.5 Clemson 11 Florida 9 Georgia 10½ LSU 9 Miami 8½ Michigan 9½ Miss St 8 Notre Dame 9½ Ohio St 10 OU 10½ Oregon 9½ Penn St 8½ Texas 9½ Texas A&M 7½ UCF 10 USC 8½ Washington 10 Wash St 8½ Wisconsin 8½— Brett McMurphy (@Brett_McMurphy) March 11, 2019In the Big 12, Oklahoma gets the highest win total with 10.5, while Texas comes in with 9.5 wins.The ACC will see Clemson dominate once again with 11 wins – a number that would seem to indicate their winning streak coming to an end.As for the Pac-12, Washington appears to be the lead dog with 10 projected wins, while long-suffering USC recovers with 8.5 wins of their own.Independent Notre Dame seems to suffer a slump with only 9.5 projected wins.Group of Five titans Boise State and UCF are slated to get 8.5 and 10 wins respectively.last_img read more

PRINCE CHARLES REVEALS HES A HUGE LEONARD COHEN FAN HE WAS INCREDIBLY

first_imgAdvertisement Advertisement Prince Charles revealed he’s a fan of Leonard Cohen as he spoke to presenter Michael Berkeley on a special edition of Radio 3’s “Private Passions”.The 70-year-old chose Cohen’s “Take This Waltz” as one of his tracks, admitting: “I’ve always loved Leonard Cohen’s voice and his whole approach to the way he sang.“He was obviously incredibly sophisticated in the way he sang, but also wrote. I find it very moving, the words are so extraordinary, sort of Salvador Dali-like, they lead you into this remarkable Dali-like world.” Prince Charles (Photo by Chris Jackson – WPA Pool /Getty Images) Twitter LEAVE A REPLY Cancel replyLog in to leave a comment center_img Charles also discussed the decline of music education in schools.He explained, according to the Guardian: “I’m one of those people who believes in the importance of arts education and music education in schools.“Apart from anything else, I think people forget – or may not realize – what an enormous contribution the creative arts make to the whole economy. It’s immense.“So we slightly shoot ourselves in the feet if we ignore it altogether. When you go to schools which still have it [music education], it is wonderful to see the enthusiasm on the part of the children in their orchestras.”The royal then said of his own school, Gordonstoun: “In those days, the early ’60s, we had these marvelous music teachers who had escaped the Holocaust in Germany and came to Gordonstoun and taught music there.”By BECCA LONGMIRE | ET CANADA Login/Register With: Advertisement Facebooklast_img read more

Swoop to target millennials young families and cross border travellers WestJet

first_imgWestJet Airlines Inc. plans to target millennials, young families and frugal travellers for its discount carrier Swoop which launches service next summer.The Calgary-based airline (TSX:WJA) said it expects to offer fares that are about half the level of the mainline carrier, but come with hefty extra fees for bags and other ancillary services.It estimates the net savings should be 30 to 40 per cent.“The core of the brand is going to be low fares and enabling people to travel that wouldn’t be able to travel otherwise or travel more often,” WestJet executive vice-president Bob Cummings said Wednesday during an investor day presentation.About 60 per cent of Swoop passengers are expected to fly for leisure travel, 30 per cent to visit friends and family and 10 per cent for business or in groups.Cummings said WestJet “ripped apart” discount airline models used in the United States and Europe and looked at lessons they learned when designing Swoop.The key is to cut costs to their absolute lowest by outsourcing jobs where possible, obtaining low airport charges and restricting sales to online transactions.However, WestJet sees opportunity in eliminating the need for Canadian travellers to cross the border to access cheap fares.Fares from Canadian airports like Hamilton and Abbotsford, B.C. are expected to be similar to those at U.S. border airports, while saving hours in traffic.“We believe this is a substantive tried and true opportunity for us to go after,” Cummings told analysts.The full cost of Swoop charges and destinations will be unveiled in February when tickets go on sale.Swoop will compete against Flair Airlines, which said this week it was lifting carry-on fees, Canada Jetlines and the prospect of Air Canada Rouge and FlyToo joining the field.At the same time, WestJet says it will go after business and international travellers by adding premium cabins with hot food, Boeing 787 Dreamliners for global destinations and new lounges at key airports such as Calgary, Vancouver and Toronto.On Wednesday, WestJet and Delta Air Lines announced plans to form a joint venture that will enhance transborder service and deepen their relationship.The partnership, which has yet to be approved, is expected to be in operation in the first half of 2019. It would increase travel choices between Canada and the United States along with enhanced frequent flyer benefits.WestJet and Delta said their preliminary agreement anticipates co-ordinated schedules for new destinations and expanded codesharing, which allows each partner to book seats on the other’s flights.The deal with Atlanta-based Delta was announced as WestJet unveiled financial targets through 2020 that analyst Doug Taylor of Canaccord Genuity said “echo well-received guidance provided by Air Canada several months ago.”“We believe this guidance should be seen positively on the margin as it confirms that WestJet’s multiple expansion programs are not going to come at the expense of near-term profitability and balance sheet,” Taylor wrote in a report.WestJet said it expects annual revenues will increase by between $300 million and $500 million through 2022 from ancillary fees, an enhanced revenue management system and broadened fare products.It has also identified annual cost savings opportunities of $140 million to $200 million over the five years from fleet reconfigurations, airport operations cost savings, optimized maintenance plans, digital self service, and sales and distribution channel efficiencies.last_img read more

Libya military police chief killed in Benghazi security

first_imgBENGHAZI – Libya’s military police chief, Colonel Mustapha al-Barghathi, was shot dead Friday in the restive eastern city of Benghazi, the security services said.Unknown assailants gunned down Barghathi outside his home, Colonel Abdullah al-Zaidi, spokesman for the security services, told AFP.He said Barghathi — a former rebel leader in the 2011 uprising that toppled longtime dictator Moamer Kadhafi — died of head and chest wounds at the Mediterranean city’s Al-Jala hospital. Barghathi was the first officer in Kadhafi’s army to defect and form a rebel force in the revolt, Zaidi said.Benghazi was the cradle of the uprising that toppled Kadhafi’s regime, but has since seen a series of assassinations targeting officers in the security services.Other attacks have targeted Western interests and diplomats, and much of the violence, including the killing of US ambassador Chris Stevens and three other Americans in an attack on the US mission last year, has been attributed to radical Islamists.The attacks have not been claimed and no arrests have apparently been made.Two years after the revolution, Libya’s new authorities have failed to establish a new army and police force, and are still struggling to rein intribal militias and groups of former rebels.last_img read more

Côte dIvoire election process moving ahead UN official reports

8 January 2009Despite some problems, voter identification and registration in Côte d’Ivoire have been positive overall in the run-up to elections, a key element in resolving a political crisis that in 2002 divided the West African country into a rebel-held north and Government-controlled south, a top United Nations official said today. “As of today, we have 3 million people identified and in a few months the identification process will be complete,” Secretary-General Ban Ki-moon’s Special Representative Y. J. Choi told reporters after meeting with Alassane Ouattara, leader of the opposition Republican Rally.The elections have already been delayed several times and Mr. Choi reaffirmed the commitment of the international community to provide the logistical, technical and financial support needed to sustain the registration process. The UN Mission in Côte d’Ivoire (UNOCI) was set up in 2004 with support for the organization of open, free, fair and transparent elections a key element in its mandate to bring peace and stability to the world’s largest cocoa exporter. Presidential and legislative elections were originally slated to take place by 31 October 2007 at the latest. read more

TransCanada sells US power plant in Arizona to Southwest Generation for 623

CALGARY — TransCanada Corp. has signed a deal to sell its Coolidge Generating Station in Arizona to a subsidiary of Southwest Generation Operating Co. LLC for $623 million.TransCanada chief executive Russ Girling says the sale, worth US$465 million, is part of a plan to help fund the company’s capital spending program.The 575-megawatt natural gas-fired power in Coolidge, Ariz., is underpinned by a long-term power purchase agreement.Under the terms of the PPA, Salt River Project Agricultural Improvement and Power District has a right of first refusal on a sale to a third party.TransCanada owns and operates pipelines across North America as well as power generation assets including a stake in the Bruce Power nuclear power plant in Ontario. read more

Extremely fragile conflictridden Burundi needs close monitoring Annan

In his latest report to the Security Council on the UN Operation in Burundi (ONUB), covering the situation since November, Mr. Annan noted that “significant challenges remain,” with the “most immediate task facing the Government is ending the 12-year conflict and restoring durable peace.” “After more than a decade of devastating conflict, the security and economic situation in Burundi remains extremely fragile, requiring massive commitment of all involved,” the Secretary-General pointed out. “Urgent improvements are required in the areas of good governance, transparency and accountability and respect for human rights, as well as the continuation of major economic, security and political reforms,” he said, stressing the importance of the active involvement of the region, bilateral partners and the UN. The conflict, along with recurring drought and frequent displacements, had driven “two thirds of the population into extreme poverty and thousands are still facing serious food shortages,” he said. Describing the humanitarian and social crises in Burundi as “acute,” Mr. Annan emphasized that the plan to fully withdraw the ONUB by 31 December had been developed with the Government, “following its specific and strong request for the early disengagement of the United Nations peacekeeping presence.” He noted that the “initial tasks” of the UN operation had been completed, but warned that “given the severity of the challenges facing the country…the possibility of a relapse remains strong,” and recommended altering the withdrawal time depending on the situation on the ground. “In that regard…it will be prudent to continue to monitor developments closely and assess the situation in the coming months, in consultation with the Government and major stakeholders,” he pointed out. “Should the situation at that time so require, the pace of the ONUB drawdown could be adjusted accordingly in full consultation with the Government,” Mr. Annan concluded. Earlier this month the UN said that 2.2 million people in Burundi — including refugees and returnees – will need food aid in 2006 because of poor rains, crop disease and poverty. read more

Parking services looking for feedback

Brock University is looking for ways to improve the parking experience for the thousands of students, staff, faculty and visitors who drive onto its several campuses every day.Brock Parking is conducting a Parking Services Master Plan survey in support of Brock’s current Campus Master Plan.The survey will go out Monday, March 28. Lot users are asked to complete the brief survey by Monday, April 4.“The purpose of this planning exercise is to receive feedback in an attempt to create a safe, sustainable and friendly parking experience for all users,” said Wendy Laslo, Brock’s director of parking and visitor services.She said the survey will help the University make sure that it is maximizing the use of parking lots. Brock has more than 4,600 parking spots in total.It is being sent out to students, faculty and staff as well as community users.Laslo said the survey is asking users about their habits, preferences and needs for the next 10 years.Questions range from how drivers want to pay to what the lots are like to navigate.“We want to make sure we are providing the best, most efficient, cost effective parking on campus,” Laslo said.The last parking survey was done in 2003, the same year that Zone 2 lots T, U and V were added.Respondents who complete the survey will be entered into a draw for a chance to win one of 10 $100 Brock Card gift cards that are valid at a number of on-campus outlets and some off-campus locations.Click here to take the survey. read more

Petrol set to go up 3 cents

first_img Facebook Twitter: @NeosKosmos Instagram Petrol prices in Australia are set to jump an extra 3 cents a litre in the next fortnight following a $5 rise in Singapore unleaded price. Last week, the average price of unleaded petrol fell 2.7 c to 142.2c and the national weekly average metropolitcan price fell 3.9c to 140.9c. Australia’s fuel prices are dependant on the Singapore benchmark as it has the regional refining and distribution centre there. While Adelaide had the cheapest unleaded petrol last week, prices fell in all major cities except Darwin and Hobart.last_img read more

Airtime ou quand Facebook rencontre Chatroulette

first_imgAirtime, ou quand Facebook rencontre Chatroulette !Les créateurs de Napster, pionnier du téléchargement en Peer to Peer (P2P), viennent de mettre au monde un tout nouveau service. Baptisé Airtime, il s’agit d’un chat vidéo permettant de discuter avec ses amis, mais aussi avec des anonymes, et ce via Facebook. Onze ans après la fermeture de Napster dans sa version originale, l’un des tous premiers sites de partage de musique en P2P, ses créateurs Sean Parker et Shawn Fanning ont développé un tout nouveau concept : Airtime. Celui-ci pourrait être simplement résumé en la rencontre de Facebook avec Chatroulette, un service qui permet de discuter en vidéo sur Internet avec des inconnus. Ce dernier avait créé le buzz, durant l’été 2010, accompagné d’une polémique : nombre de personnes inscrites utilisait le chat comme un outil d’exhibitionnisme, alors que le but premier du service était de permettre de nouvelles rencontres.Airtime vise le même but, tout en évitant les mêmes dérives. Le service propose une messagerie instantanée grâce à laquelle les internautes pourront discuter avec leurs amis sur Facebook et, surtout, avec des utilisateurs qu’ils ne connaissant pas. Il permet alors de connecter des personnes en fonction du lieu où ils se trouvent et de leurs intérêts, indiqués sur le réseau social, tout en leur laissant la possibilité de ne pas révéler leur identité.À lire aussiMaladie de Charcot : symptômes, causes, traitement, où en est on ?Sean Parker, qui fut le premier président du réseau social de Mark Zuckerberg, a expliqué comment lui était venue cette idée lors d’une conférence de presse rapportée par Bloomberg. “Facebook ne vous aide pas à créer de nouvelles connexions, Facebook ne permet pas de développer de nouvelles relations, a-t-il souligné. Une partie de moi-même se sent quelque peu ennuyée par tout cela. Il n’y a pas de place pour la sérendipité”.Cettefois, a promis Sean Parker, une “tolérance zéro contre les comportements inappropriés” seraappliquée. Mais voilà que cet engagement pose déjà problème. Car pour interdire ces “comportementsinappropriés”, il faut les surveiller. Chose qui n’a pas échappée à la journaliste Kashmir Hill. Sur le site de Forbes, elle indique que la chat Airtime pourra enregistrer les discussions de ses utilisateurs. “En utilisant notre service, vous consentez à avoir votre image et vos conversations enregistrées par Airtime. Airtime prend des instantanés de contenus utilisateurs et peut le vérifier pour maintenir la sureté du site et assurer une bonne expérience utilisateur” lit-oneneffetdans les règles de confidentialité du service.Le 6 juin 2012 à 21:00 • Maxime Lambertlast_img read more

Adam Rose and Konnor suspended for 60 days by WWE for second violation of…

first_img April 17, 2016 at 2:54 am Facebook brought me here. Also,what were theses Adam Rose and Konnor thinking?! Google+ Facebook WWE issued the following press release on Saturday afternoon confirming 60 day suspensions for Adam Rose (Raymond Leppan) and Konnor (Ryan Parmeter) for a second violation of the company’s Talent Wellness Program.WWE SUSPENDS RAYMOND LEPPAN AND RYAN PARMETERSTAMFORD, Conn., April 16, 2016 – In accordance with its Talent Wellness Program, WWE has suspended Raymond Leppan (Adam Rose) and Ryan Parmeter (Konnor) each for 60 days effective immediately for a second violation of the company’s policy.About WWEWWE, a publicly traded company (NYSE: WWE), is an integrated media organization and recognized leader in global entertainment. The company consists of a portfolio of businesses that create and deliver original content 52 weeks a year to a global audience. WWE is committed to family friendly entertainment on its television programming, pay-per-view, digital media and publishing platforms. WWE programming reaches more than 650 million homes worldwide in 25 languages. WWE Network, the first-ever 24/7 over-the-top premium network that includes all live pay-per-views, scheduled programming and a massive video-on-demand library, is currently available in more than 180 countries. The company is headquartered in Stamford, Conn., with offices in New York, Los Angeles, London, Mexico City, Mumbai, Shanghai, Singapore, Dubai, Munich and Tokyo.Recommended videosPowered by AnyClipBully Ray Calls Out Ring Of Honor Fan On TwitterVideo Player is loading.Play VideoPauseUnmuteDuration 0:30/Current Time 0:04Loaded: 100.00%0:05Remaining Time -0:26 FullscreenUp NextThis is a modal window.Beginning of dialog window. Escape will cancel and close the window.TextColorWhiteBlackRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentBackgroundColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyOpaqueSemi-TransparentTransparentWindowColorBlackWhiteRedGreenBlueYellowMagentaCyanTransparencyTransparentSemi-TransparentOpaqueFont Size50%75%100%125%150%175%200%300%400%Text Edge StyleNoneRaisedDepressedUniformDropshadowFont FamilyProportional Sans-SerifMonospace Sans-SerifProportional SerifMonospace SerifCasualScriptSmall CapsReset restore all settings to the default valuesDoneClose Modal DialogEnd of dialog window.Replay the list Now Playing Up Next Cameron Huff Videos Articles Velvet Sky April 17, 2016 at 3:14 am Live Podcast: Reviewing and discussing WWE Clash of Champions from Charlotte Thomas Costello Dear! This is terrible! Poor kid. WhatsApp April 17, 2016 at 1:41 am Pinterest April 17, 2016 at 3:34 pm Wrestleview Live #65: Reviewing and discussing WWE Clash of Champions from Charlotte April 16, 2016 at 7:29 pm They only keep Adam around because of his kid. Twitter Bully Ray Calls Out Ring Of Honor Fan On Twitter Now Playing Up Next April 17, 2016 at 11:42 am April 18, 2016 at 10:00 am Matt Demarle Now Playing Up Next Ronda Rousey On WWE: I Love This Job, But I Dont Need It Glen Värîs Glen Värîs Ronda Rousey Highlighting WWEs Problemscenter_img OH NO! With all your stars down with injury you suspended two more top tier talents??? Aaron Rose and Konnan fow two months? I mean, how are you going to expect Joe Everyfan to continue watching Raw and such without main eventer’s like this? Oh well maybe the other demolition warrior/Kevin Sullivan dude can have a decent singles run… Vince Matt Demarle Oh well there goes their pushes. He was born with his liver and intestines outside of his abdomen and needed corrective surgery. https://youtu.be/s3MFI21wqss?t=12m14s Clash of Champions Highlights: Luke Harper returns, Rollins/Strowman, Becky against Sasha Matt Demarle April 17, 2016 at 3:48 pm Now when they get back there careers will be buried. Oh wait!!! TheCyberZon 12 COMMENTS yes….ironic really…. Adam Martin RELATED ARTICLESMORE FROM AUTHOR April 17, 2016 at 2:55 am Looks like there is going to be need for another Social Outcast. If Crush was still around they could put him in as the third Ascension member like they did back in the Demolition days. I think they should have kept Connor until Monday an had Anderson and Gallows destroy them to get them off TV. Seth Rollins Defends WWE On Two Separate Occasions Comments are closed. Vince April 17, 2016 at 10:31 am Too much irony spoils the irony… April 16, 2016 at 5:41 pm Cedric Anthony Now Playing Up Next Whassup with his kid? Roman Reigns is in Remission April 16, 2016 at 3:47 pm Mat Thompson Now Playing Up Nextlast_img read more